SP5.1.4 A meta-analysis on the impact of bariatric surgery on lower urinary tract symptoms in men

Abstract Background Obesity is a chronic disease with multisystem morbidity. There are multiple studies reporting the effect of bariatric surgery on cardiovascular and metabolic but only few examine its impact lower urinary tract symptoms. This article aims to perform systematic review meta-analysis in order determine effects symptoms male patients. Methods Medline, Embase, conference proceeding reference lists were searched for quantative measurement score pre- post-weight loss surgery. The primary outcome was International Prostate Symptom Score (IPSS) before after Secondary outcomes change Body Mass Index (BMI) Total Weight (TBW). Weighted mean differences (MD) calculated continuous outcomes. Results Seven included analysis 334 patients undergoing Mean study follow-up between 3 36 months. statistically significant improvement IPSS following (MD 2.82, 95% CI 0.96 4.69, p = 0.003). Bariatric also resulted reduction BMI TBW. Conclusion produces men obesity. may be due insulin sensitivity, testosterone levels or lipid profile associated weight loss. Further necessary investigate detail pathophysiological mechanisms through which develop obese patients, their